This is purely speculative of course, but if the character Ryce is hinting at is Pyron, he could be Capcom's comic level counterpart to Thanos, since everyone assumes Thanos is going to ultimately be a larger threat than Ultron and Sigma. Pyron isn't dissimilar to Galactus in the Darkstalkers universe, and if you want Thanos to "merge" with a Capcom villain it wouldn't be farfetched for him to absorb Pyron's power with minimal design changes.
Granted, this makes a LOT of assumptions, some safe and some less so (that Thanos is returning, that he would be the main villain, that he needs a Capcom counterpart, etc). But if Thanos IS going to be the lead villain, it does seem weird to have such an interesting combo subvillain and then have the main villain only represent one of the two companies.
EDIT: In theory, if you have two hybrid villains they could both be made playable without unbalancing the roster count. But that's getting WAY ahead of myself.