Just finished the game today. Had so many games on my backlog that it took awhile to find time for this. Anyway, I read the first few pages of the thread and I agree with the sentiments of most people.
Talbot and Marlowe: I would've liked some more backsight on their relationship and who they are. I got more Cutter than I really wanted, and would have preferred more on them. Especially at the end when Talbot is all distraught after Marlowe dies.
Drake and Elena: Obviously these two love each other, and despite some very endearing moments between the two of them, it felt a little weird that there was never more than an embrace between the two of them. Not saying they needed to imply a love scene ala UC2 between Drake and Chole, but after Drake reconciles with her at the end of the game he simply hugs her? Felt a little off. Unless these two are against PDAs, why not cap everything off with a kiss between the two?
The action this time around was as good as ever. The airplane level was incredible. I literally screamed out loud when Drake fell out of the plane and grabbed that cargo with the parachute. The desert level was just long enough. Any longer and I would've been sick of it. Hope next time ND doesn't do the whole mythical city at the end. It's kinda lame at this point. Especially since these cities always seem to implode.
The hand to hand combat and enemy types needs an overhaul. As someone else said, the combat with the big guys was far too repetitive. The instance in the bar was cool, but after the fifth fight with a big it got kinda lame. Same thing for steel plate guy.
Overall, an okay Uncharted game is still better than most games. Hope ND takes what seems to be universal criticism to heart and makes some tweaks for the next game. Heck, just copy Arkham City's combat hand to hand combat system.