Mako Video: https://www.youtube.com/watch?v=MzueBbcXqRk
Via tweets about the panel:
I'm tried to put non-obvious details/newer stuff near the top of the list.
-The Mako is back, they showed video of it, and there are images of it below. It's apparently quite fast now.
-"Building a game about exploring places, so you need a vehicle for that "
-"We learned some things about vehicle frustration"
-They showed off armor renders, viewable below
-"Sounds like the timeline of #MassEffect will be during Shepard's lifetime but won't involve Shepard...hard to tell @GambleMike being cagey!" [Note: Two other tweeters said it sounds like it takes place in another galaxy, though that's not necessarily mutually exclusive with this.]
-"Team reiterates that it is not Shepard's story and that this story one is brand new."
-"no timeline was announced at the panel. Some hints were made but I have to re-listen to the audio."
-"You will see a bit of old with the new (old characters MAY appear) "
-"Competition is critical but cooperation is bigger for us" @GambleMike speaking on multiplayer in #MassEffect / "cooperative MP is bigger for us (than competitive)"
-"Spiritual successor" vibe for the next
-"It's ingrained in us to give players as much choice as possible" - @GambleMike #MassEffect
-"The animation team is now doing stuff we couldn't even dream about before" speaking on Frostbite 3 for #MassEffect
-"it's not called ME 4 damn it! " [I'm going to keep calling it that until they give it a name.]
-No announcements on player race choice of composers when asked
-The internet kept dying for the people livetweeting so there are more details that aren't here
-"I got video of the new #MassEffect Mako in action"
-"Seems strongly implied that new Mass Effect will be set in totally different galaxy, but will contain familiar elements. #SDCC"
-"Not playing as Shepherd, and Shepherd is not important to story - new uncharted areas. #SDCC"
-"Mako is back in Mass Effect! More agile, no cannon. #SDCC"
-"New Mass Effect is focused on exploration of planets, Mako is meant to be fast travel on them. #SDCC"
-[Note]: Nerd Appropriate (one of the original tweeters) also said it sounded like another galaxy but they need to double check their audio recording.