If Nintendo can get Arms and Splatoon 2 out by May and June, then announce a fresh 2nd half line up at E3. We will be in good shape.
Ya know, I'm as excited as the next guy, but after how light on content the January presentation was, I'm not holding my breath for megatons at E3. I'm sure there'll be one or two new announcements, but I'm expecting a Smash 4 port and maybe Pokémon Stars and Monster Hunter XX
at best. Like, I'll consider it decent if even one of those games is announced. The rest I expect to be (more) detailed online plans and release dates and footage of stuff we already know about. Heck, I'm even expecting coverage for stuff that will already be out by then. That's it. Oh and maybe a "Metroid in 2018 but we've got nothing to show for now" if Nintendo uncharacteristically feels like giving us some visibility into the next year.
I hope I'm wrong, but I know the pattern now: take your lowest expectations, and then make them even lower to avoid disappointment.