Theres definitely something wrong with the battery usage. Its been five days since I updated to the GM and its still draining like crazy.
My iPhone 6 Plus updated from 10.3.3 to the GM accrued over 5 hours of battery usage overnight. In comparison, my iPad, which was updated from beta 10 to the GM only accrued 3 min.
My iPad used to have pretty bad battery life earlier in the betas but that seems to have gone by now.
I cant figure out whats causing the usage. Unless background tasks after update really takes this long to do its thing, this drain is horrendous. I went from 36-40 hours standby before needing a charge to now needing a charge at 20-22 hours standby.
I thought that was one of the big new things in Series 2, improved battery life? If so it probably wouldn't be quite as noticeable on those devices compared to the Series 0.
But after looking through all the settings it appears you can disable the new resting heart rate feature. It's just hidden away in a weird place under the "Privacy" section of the Apple Watch companion app. I toggled it off and hopefully it'll improve the battery life.
Apple Watch has always measured your resting heart rate at regular intervals. Im pretty sure those toggles in your screenshot have always been there. I doubt thats the cause of any battery issues, unless they increased the frequency of measurements.