IQ and resolution wise obviously UC4 will obviously be destroyed by high end PC games. But a lot of the stuff they are doing with interactivity and animation is seriously far beyond anything I have seen.
Well, I guess you can say "destroyed" is very subjective and variable. I would say that if you render a game at 4K or downsample it from 4K, then the IQ would "destroy" Uncharted 4's IQ. But yeah, judging from the beta, Uncharted 4 had pretty damn good IQ and that was 900p. The campaign will have even better IQ.
It looks absolutely fantastic. I love everything they are saying and loving that they dialed back up the stealth. Though there was one unfortunate part where they say the enemy is smarter now but show Nate doing a take down on an enemy close to and within the peripheral vision of another who doesn't notice. That's not great AI for stealth but a small niggle I guess.