So, honestly, the entire confusion around this situation is pretty ridiculous. Coming out as transgender and admitting that you're considering transitioning is a hell of a thing to do, especially when you're in the public spotlight, but if that is now for sure the situation (and hell, I'm still a bit confused really), her wishy-washiness about everything just made things worse, not better. Being so back-and-forth and uncommitted on answers isn't the kind of image you want to portray to people of how trans folk are.
As hard as it might be, be proud of who you are and admit to it. Yeah, she's in the public eye, but she's also got enough money to not have to worry about how to survive while transitioning, something most TG folks don't have the luxury of. Plus, unlike the gay community, trans folks have little to nobody to look to as examples of well-known people who are trans.
Didn't know about Tykwer, I really liked Lola run and especially Perfume, I believed it was unfilmable before seeing it, but I feel Cloud Atlas resonates better with the Wachowskis. I could be wrong again.
Regarding the shoot, they may have added a story or maybe moved the korean chapter in iraq. And given the theme of the book that wouldn't really change a lick.