I think I'd say Gillan Anderson as Scully from the X files. Yeah, she wasn't an alien but she was in a show about aliens.
I'll give you that she's an alien in 'V'. Like the main alien. At least I think she is as I only watched two episodes.
Looking forward to the Klingon Rule 34 to come from this new horrible movie. It's out already, right? Did they update the image, because female Klingons were attractive in the Original Series.