No, the usual benefit of not losing tracking when moving around too much but not more than that. Sometimes you have enemies coming from 2 opposite sides so you can extend your arms to the sides and shoot them at the same time (maybe also doable with move controllers if you can keep your controllers in the viewport of the move camera) and you can shoot your gun behind your back, but the game is not build around doing things that would occlude your hands, it's originally developed for a front facing set-up I believe.
The game is on the short side of VR games though, even taking many of the experiments and early access stuff into comparison so I would temper my expectations (under 2 hours and I was done with the "campaign") you can add more hours with challenge modes and so on but that depends on if you like what's there.
For my personal taste it's a little bit too simple of a game to dive into headshot challeneges and speed runs but many people seem to love it.