I'll complete my first year of my first post-doc in two days. Coincidentally, I'm sending out my first (and only, for the near-future) application for a tenure-track faculty position in microbiology. It's a little early as I don't have any good project to take with me from my post-doc work yet, but I have a good project to build on from my graduate work, and am going to meld my post-doc experience so far with my experience from grad school for two other project directions. This should give me one strong research direction with two good additional directions which are somewhat secondary/only partly tested in-lab.
I think I have a great chance to get an interview, but worry that my research talk/chalk talk won't be strong enough if I make it that far in the process. I am applying to an R2-level school, so hopefully this means I can get at least to an interview. My teaching experience is pretty strong, especially with undergraduates, so that'll help me a lot at this school.
What I feel very good about are my papers and grants. I'm up to 17 publications now (5 first author, one of those a review) with 2 (hopefully 3 by the time I apply) more under review (all being first author). Then I've gotten 2 grants as the PI totally about $230,000, which I have to believe is far beyond the average for most applicants to an R2's assistant professor-level call for applications.
Anyway, wish me luck folks. Got a few more weeks to write up my application materials, then some waiting and crossing my fingers for a call to interview.