Grr. It is Punkbuster that was causing me issues before. Soon as I installed BC 2 and played (and reinstalled that Malware crap), I come out of sleep, and the computer hard locks. DVD drive has running (nothing in). Who knows what the hell it was trying to do.
Had this problem when I played the MoH beta. Nailed it down to either my Razer mouse drivers (which worked perfect till then), the Firefox beta, or Punkbuster. Thought it was Punkbuster But I forgot about it. And it's been months of smooth sailing. Till now. It's back. If there's not a way to disable that crap and not have it load at startup, that's 20 bucks down the drain.