I wish they had wrapped up Cait's story in 5,i just don't really find her that interesting of a character. Not that JD or the rest is super great, they are ok. It will never get close to the old crew, that's for sure.
I also hope they do more with the big open areas this time. Honestly wish they didn't bother at all with them, Hivebusters showed that it really isn't needed. Give me a full game like how that expansion was and we good!