I've used Okcupid and POF. I think Okcupid has far and away the best matching tools of any dating site, if you're willing to answer 100+ questions with your honest opinion. Of course, I'm looking for a relationship, not something casual, so I find that that's the best environment for me. In my time looking at Datehookup, it's half way between adult friend finder and POF.
And POF isn't that good. Too many girls barely fill out their profiles. Or throw out cliches ("I haate talking about myself, down to earth, work hard play hard, laid back, chill, drama free, looking for a real man, etc") and top off with "if you want to know more message me." Well, I practically know nothing about them, so no, I don't want to spend my time crafting a message for someone that doesn't even care enough about finding someone to properly describe themselves. It's also kind of bad about giving you girls to look at that are within close proximity. Unless you want to sort by distance and go through 70 pages or more, just to see what's out there. You'll get little to no matching help with POF. Yet, I use it because there isn't much crossover between POF and Okcupid.
So far for me:
Okcupid: 1 date that was nice enough, a few random messages from some girls that I didn't find too attractive, messages sent and left unresponded to by 8+ girls.
POF: 0 dates, though lots of chatting with one girl who has no plans to ever meet up. Another 6+ messages sent with no response. Some girls that were slightly crazy or unattractive messaged me. When the 6th obese girl messaged me I finally had to include a polite "no fatties" cliche at the end of my profile.
That's my experience. If I sound slightly downtrodden, it's because I'm the guy that actually writes personalized messages for girls and still gets no responses. To the point where I don't know what I'm doing wrong, besides that I should go put on some muscle or something at the gym.
All the same, I wish you and others good luck.