Not having enough time for gaming.
This. So many awesome games, tons of rpgs and open world games and no time to play them. I can play city builders or turn based games at work since i work at home and have my pc next to my work pc. I can get a turn or two between clients and calls, but its not the same as dedicated time.
It's also why I have shifted away from console and pc gaming (except for a few hours on the weekend) to gaming on switch/switch2/steamdeck. Playing handheld with pause /resume on power off, I can play for a few minutes no matter where. On the toilet, yeah I can grind a few battles out in a jrpg or play a few metroidvania areas. On the porch, while cooking dinner, etc.....
Also once you get married (or even worse if you have kids. Did that already, with my first wife, 2nd wife no kids but still no time) your time goes down for gaming drastically, unless they too are into gaming.
My wife is into other types of gaming, board, card, physical outside non organized sports, and stopped buying consoles with the wii (she has a gamecube and wii and was a nice bonus playing games I never had).
You have to dedicate time to your wife after work (if you don't say bye bye to said marriage, and i am not talking about just sex). This time takes away from gaming. So again this is where the switch helps out, big time.
I can be on the couch playing a game on my switch while she watches her shows. It's a win win. Thank you Nintendo (and playstation before 2017 for vita and psp), portable systems are not just for kids.
My hope is my hands, and brain still works by the time I retire and I am not in constant pain so I can play all these games I never finished. One problem, the switch and my collection will probably fail with its battery long before 20 years from now.