Armoured Priest
Member
Alucard is ass. It's not worth getting him unless you just want a challenge because the path you take to get him is easily the hardest path in the entire game. One might say that path is unfairly hard. If you get him his fly ability is only really useful for the final stage and if you want to bypass the clock tower platforming.
Sypha (who is definitely female, watch the end cutscene)is okay. At one point I thought she was the best but in order to make her useful you have to get that Freeze spell and to do that you either need to have memorization of the levels and what candles have what or constantly switch back and forth from Trevor to her which isn't very fun. Her Freeze spell is really, really good and makes flying enemies and those unkillable spark balls on platforms trivial. But, once you die with her you lose it so there's definite minuses. Her fireball attack is okay but it does only slightly more damage than Trevor's whip. I think she has a homing attack which is very good but it's very rare and personally I don't think it's as good as the Freeze spell.
Grant kinda' breaks the game. In Japan he was the best character because his default attack was a throwing dagger that went fullscreen. It didn't do as much damage as Trevor's whip but it still one-shotted a TON of annoying flying enemies. But even in his nerfed American incarnation (without the throwing dagger) he's easily the best character because he trivializes a lot of platforming sections, his health is on par with Trevor, and he can fully control his jumps ala Castlevania 4. Plus you can mix and match subweapons. Want to keep the Axe for Trevor and the Stop Watch with Grant? Go right ahead.
Short version: Grant is the best partner.
For extra fun, try running the game without picking up a partner. ;P