Fucking Mortal Kombat.
I think I remember (not sure, but I'm pretty sure it happened) reading an interview where Ed Boon was laughing/taunting/trolling about the boss difficulty in MK9, calling it a throwback to the early days of fighting games. Which pissed me off all the more, because its one thing to play off nostalgia, but to implement gameplay that was shitty then, and is even shittier now, all for the sake of nostalgia? Fuck you. There's a multitude of shitty, douchey things Ed Boon's said/done, but making his MK reboot a frustrating, cheesedick gaming experience for no other reason than he thought it'd be funny to imagine millions of gamers chewing on the side of their controller/fightstick in rage while he settles in for a long night of jerking off into his ridiculous fucking eyebrows?
Maddening.
When the whole point of the game was to eat millions of dollars in quarters in an arcade? Yeah, input-reading, no-selling bullshit is understandable. When you're going straight to consoles and the entire industry has shifted away from that model? Pointlessly stupid. But intelligence is never anything either Boon or Mortal Kombat has worn very well.
2nd place is Blue Shell. 3rd place is those goddamn birds in Ninja Gaiden.