This is a weird thread to read simply because the experiences described by some couldn't be more different at times. Infamous is someone's "most glitchy" game? That's insane. I've played through that game multiple times and I didn't even know there were glitches.
To the question though, Bethesda is the easy answer, and more specifically this gen's Fallout titles. Gamebryo (I think that's the engine name) is so horrendously prone to glitches, it's barely acceptable. Thankfully, through frequent saving I never ran into a problem I couldn't fix. (Though Skyrim actually bugged out a few missions to make them unfinishable.)
My most frustrating glitch was ZombiU though. There is a point where you need to pick up a gas can tucked away in a corner. If you walk past it and leave the area, the gas can disappears. Since the game has only one save and auto saves constantly, you can't progress and can't reload. When asked about a patch Ubi basically shrugged its shoulders. Unbelievably frustrating. Had to restart the whole game after 7 hours of very intense play.
Edit: Totally forgot the new Xcom! I love that game, but the glitches make Ironman mode a very broken experience.