Here are some of my recent favorites:
G.I. Joe COBRA Vol. 1
Story by Christos Cage and Mike Costa
Art by Antonio Fuso
Not being a fan of G.I. Joe in the slightest, I pretty much avoided this book like the plague. But I'll be damned if every comics journo on the planet wasn't gushing about it. Eventually I just gave in and gave it a read, and I'm so glad I did. The story takes place just as Joe is getting off the ground, and before Cobra is a known entity. Chuckles, a gifted field agent with a talent for pissing off his superiors, gets taken off of Joe and re-purposed as a spy. His first mission? He has to infiltrate a small terrorist organization the government's been keeping tabs on. And it just gets fucked up from there.
Locke & Key
Story by Joe Hill
Art by Gabriel Rodriguez
If Steven King wrote comics, these are the comics he'd write. "Joe Hill" is actually Joseph King, so I guess that makes sense. Locke & Key tells the story of the Locke family moving into the town of Lovecraft after having suffered a terrible tragedy. Naturally, they take up lodging with their uncle, who lives in the mysterious Keyhouse. But something's not quite right, and the Lockes are in for more than they bargained for. This book is totally worth it if you're a Steven King fan, a horror/mystery fan, or if you just dig a good read. I can't really do this book justice without dropping some major spoilers, so you'll just have to trust me - this book is crack on Scott Pilgrim levels.
Local
Story by Brian Wood
Art by Ryan Kelly
I picked this up after all of the fanfare the hardcover got last year, and it was probably one of the best reading experiences I've had in years. It's a bit of an anthology, with each story taking place in a different town that the central character's moved to, but there's a strong theme of trying to find oneself present throughout. If you've ever wanted to escape your life and start over in a new town far away, then this book is for you.
The Nobody
Story and Art by Jeff Lemiere
Jeff Lemiere's getting a lot of attention now for work on Sweet Tooth, and most people who've been keeping up with him are probably going to recommend The Essex County Trilogy (which is also great), but most people seem to gloss over Lemiere's first work for Vertigo, last year's The Nobody. As you might be able to guess by looking at the cover, our (sort of) central character is the famous Invisible Man. There's no origin story to be found here - the book begins with him shuffling into town, and pretty much keeping to himself. But when he befriends a local girl, things get way out of hand. Lemiere does what he does best here - he takes a small town and gives it a heartfelt story, and the result is spectacular.
I know I'm forgetting a ton or recent stuff, so I'll add more later.