Feel bad reading that article, like the vibe is "we've done so many great games but somehow amazing success has always eluded us". Either with collabs that end up amazing but Obsidian never really gets its due - Southpark comes to mind - or games that are pretty good, but never really bubble into that top tier elite stratosphere of games, like GTA or COD or Battlefield or Mass Effect.
Its gotta be super tough to be a mid sized developer. With a small team you are rolling the dice on your game doing well, but you don't need to really sell that many copies each time to get another shot. Large scale developers have a pretty focus-grouped path to making games that sell 5m+ copies each, while you can't stray too far from what people expect, if you manage it well you are always in the spot light and you can count on a certain threshold of sales.
None of those safety nets for mid sized, you could make a great game and nobody pays attention. You could make a shitty game and not sell enough to cover its costs and have nothing to fall back on. And you won't really know for 3-4 years of insane risk how it ends up.
Its crazy the guys who did KOTOR 2, Alpha Protocol, Fallout New Vegas, and South Park aren't drowning in success, makes me feel sad