found this interesting article
http://www.thefuturereport.com/story/science-134
A couple of snippets from the story
Scientists at Imperial College London and Johns Hopkins University have made a medical breakthrough, discovering that removing the cholesterol from the HIV virus membrane disarms it, allowing for them to finally start development on a possible vaccine.
Removing the cholesterol from HIV cells means the innate immune system would not over-react, allowing the adaptive cells to form a proper and specialized cell to fight off the HIV pathogen.
They removed the cholesterol by injecting various concentrations of beta-cyclodextrin (bCD) into the cell, which causes the cholesterol deposits to bind together. Once they extracted that bit, the cell was then essentially left with a gaping hole and became inoperable because it could not stimulate pDC cells. A point to note is the fact that cholesterol in HIV cells is not the same as the one associated with clogged arteries and heart problems.
sounds like a huge breakthrough hopefully something comes of this.
Additional links
http://news.yahoo.com/scientists-way...210805678.html credit insane metal
http://bloodjournal.hematologylibrar...44218.abstract (research paper) credit Lesath
http://www.thefuturereport.com/story/science-134
A couple of snippets from the story
Scientists at Imperial College London and Johns Hopkins University have made a medical breakthrough, discovering that removing the cholesterol from the HIV virus membrane disarms it, allowing for them to finally start development on a possible vaccine.
Removing the cholesterol from HIV cells means the innate immune system would not over-react, allowing the adaptive cells to form a proper and specialized cell to fight off the HIV pathogen.
They removed the cholesterol by injecting various concentrations of beta-cyclodextrin (bCD) into the cell, which causes the cholesterol deposits to bind together. Once they extracted that bit, the cell was then essentially left with a gaping hole and became inoperable because it could not stimulate pDC cells. A point to note is the fact that cholesterol in HIV cells is not the same as the one associated with clogged arteries and heart problems.
sounds like a huge breakthrough hopefully something comes of this.
Additional links
http://news.yahoo.com/scientists-way...210805678.html credit insane metal
http://bloodjournal.hematologylibrar...44218.abstract (research paper) credit Lesath