Doubtful. Being able to problem solve and learn from mistakes is a HUGE part of gaming. After one, MAYBE two instances of "Oh ok if I touch those guys on the wire they hurt me" you should not continue to plow through them to get past those segments. So even if you miss the very obvious puzzle in the first wire area that teaches you to avoid them, you should know by the time you get to the second area NOT to touch the little black things on the wire, and maaaaaaybe pay attention to the fact that the wires split into different paths that don't have enemies on them.
Watching someone make the same mistake multiple times in a row for six and a half minutes is frustrating and indicates the person playing isn't paying attention or trying to learn the gameplay mechanics. I feel like even someone who has never played a Mario game in their life would figure out eventually not to just force their way through the bad guys after touching them a few times, let alone someone who is part of a gaming channel.