The placement of the buttons is pretty bad and so is that excuse of a d-pad. Playing Axiom Verge was murder on my fingers. I was hoping that the Switch could be my side-scroller/ indie machine replacement for the Vita but jesus, playing it is really uncomfortable. I haven't had any problems with 3D games so far, but this is the reason why I'm buying the side-scrollers and other 2D games on my PS4 if given the choice. Otherwise, I'm just not going to buy them.
Stop trying to be different in all the wrong ways, Nintendo.