Let's see.
Lolicon and moe characters and themes.
The related incursion of ecchi and hentai tropes into what would have been all ages material in the past.
Androgynous teenage heroes.
The near mandatory presence of idols, maids, hostesses, yamato nadeishiko, and other weird sexual baggage.
Ruminations on the importance of friendship or having a dream.
Virtuous kids fighting evil adults with the power of said friendship and dreams and winning.
The Japanese habit of constantly parroting a statement back as a question in conversation.
Ludicrous names for characters, places, and story concepts that are obviously the result of someone picking up a Japanese to English or Japanese to Latin dictionary and going at it.
Animal mascots.
Weapons, costumes, fighting styles, and so on with no basis in realism or regard for the laws of physics.
The way nearly all of the localization teams are staffed today with ascended neckbeards who think they're writers in their own right rather than conduits and like to "punch up" the script with coarse or sexual language, jokes and puns that weren't there in the original, shout outs to their friends, anachronistic references to other nerd media and Internet memes, and otherwise alter the tone of the work for no valid reason.
The way most Japanese games are dubbed by the same cabal of a dozen or so people.
The way most Japanese games are still built like it's 1995 with static rooms loaded one by one rather than employing streaming, open worlds, and other modern techniques and the way that limits the scope and ambition of both the games and their storytelling.
The wooden, static animations such games use over more modern blending systems.
The use of an anime art style in such games as a crutch because the developers don't want to learn how to use shaders, caustics, and other modern lighting techniques. (Anime style is not inherently a crutch, however.)
All that and the amount of "glam" the characters are designed with. I don't need fashion rejects.