1) Missing in all of this talk about whether it is harder or easier to score nowadays is any discussion of the illegal defense rule change... previously, the rotating, extremely complex, stifling system defenses of today's Bulls, Celtics, and Spurs were illegal - the best you could do would be to tightly double the ball handler and then immediately go back to your man - you couldn't cover a space on the floor or rotate around to another spot on the floor, that was illegal.
This made offense extremely broken, especially for really strong, tall people. Centers haven't "died out," the rules have just changed so that defenses don't have to be forced incentive-wise (because of the ease with which in-out passing could exploit double-teams in the illegal defense age) mindlessly single cover people in the paint all of the time, which was one reason why centers were so dominant and mostly the superstars before 2000. So if big guys are superstars now, it's because they are at least incredibly skilled to go along with how gigantic they are (Kevin Garnett, LeBron James).
Now, Mike was a freak and a god, but i think, while handchecking probably made things harder for him, the illegal defense rule probably made things easier, too. Handchecking or no, he still got a million FTAs a game, which, coupled with his strength and finishing ability (not so much his outside shooting), made him legendarily efficient.
2) To the person who said Wilt averaged 50 and 20 and we should be really impressed: Other than the fact that he played in a league where probably 90% of the players would never make it in today's league, they played at an absurd, turbo-pace where, if you adjust for possessions, his averages are certainly good but comparable to today's superstars.