I did you a little better and made a top five. I didn't link to the locations that the solos start because I consider context important, but I indicated at what time that they started if that's all you're interested in hearing.
1. http://www.youtube.com/watch?v=7a_8F6gflxQ
The Beatles - The End. Solo section is basically the whole song, they begin at about 0:20.
This is most certainly a context track. What you have here is three very different musicians playing three very different things over the same progression and on the same instrument. The mix of technical (Harrison), rhythmic (Lennon) and melodic (McCartney) aptitude produces something incredible. Every musician interested in the rock lexicon should be familiar with this piece.
2. http://www.youtube.com/watch?v=9mPNPIfEPNk
Jaco Pastorius - Dear Prudence. The solo is heavily integrated into the head, so it's basically the whole song.
The fusion of the guitarist and his rhythm section is what makes this. Simply by altering his division of time, he moves this song into a completely different territory over this six minute recording. He has the advantage of playing with a man who is arguably the greatest bass player of all time, and he uses that advantage to push the rhythmic and then the melodic basis of this piece very far out of where it once was. Truly brilliant.
3. Cannonball Adderley - Rumpelstiltskin
I couldn't find this on youtube, but I'm getting on it.
4. http://www.youtube.com/watch?v=mFpLLumawmQ
Chicago - 25 or 6 to 4. Solo begins at 1:58
This solo is rock in top form. The way that it builds in intensity is absolutely brilliant; the division of the section into three distinct but related 16-bar solos is fantastic and absolutely significant for a rock solo due to the common trend of simply running through the progression with a bunch of indistinct pentatonic/blues phrases. He plays outside of the key just enough to keep the monotonous, descending bassline interesting. Much credit needs to be given to the drummer for matching the intensity of the guitarist.
5. http://www.youtube.com/watch?v=qttI6oytqpw
Blue Oyster cult - Flaming Telephaths. Solo begins at 2:19
This may be cheating a bit because the solo is actually three different solos, but they clash so wonderfully that I'm going to ignore that for the purposes of this thread. Very rarely do rock musicians directly play off of each other like this but I truly love when it does happen. Very good use of the guitar's range to build tension. Not as spectacular as any of the other ones that I've named, but good nonetheless.
Honourable BtBAM mention is Informal Gluttony.
And that John Paul Jones bass-line is SICK!
