My big hope for E3 was more Atlus on Wii.... this was the last thing I wanted.
Stile is OK, but I don't like that other character design at all. I'm sure they're hoping that making it less anime will make it more mainstream in the US, which is probably right. I think there are a lot of people out there who'd like a surgery game who are much interested in American medical dramas than anime, and oddly enough no US 3rd parties have tried to make a surgery game with a tv license.
16:9.... that's awesome for everyone with a widescreen tv, but the majority of us, without one, will be stuck playing this 2-d pointing game in a letterbox. Not cool.
And I doubt I will get many opportunities to use the coop.
I still bet the game will be awesome though.