People think that gif is simply looping, but he went on like that for almost a minute
The only context Ive seen it used in is a hypothetical nuclear holocaust. Other than that, whatever the origin of the word it almost always refers to the crimes the Nazis committed to Jews and other groups in WW2.
And a nuclear holocaust is an appropriate terminology. There is no way one could say:
The word holocaust is used regularly without referencing the WWII massacres.
Because that is not how the word has been used in World War II.