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Harvard bioengineers create cyborg tissue, half living cells and half electronics

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XiaNaphryz

LATIN, MATRIPEDICABUS, DO YOU SPEAK IT
Harvard creates cyborg flesh that’s half man, half machine:

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Bioengineers at Harvard University have created the first examples of cyborg tissue: Neurons, heart cells, muscle, and blood vessels that are interwoven by nanowires and transistors.

These cyborg tissues are half living cells, half electronics. As far as the cells are concerned, they’re just normal cells that behave normally — but the electronic side actually acts as a sensor network, allowing a computer to interface directly with the cells.
In the case of cyborg heart tissue, the researchers have already used the embedded nanowires to measure the contractions (heart rate) of the cells.

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Cardiac cells, with a nanoelectroic electrode highlighted

To create cyborg flesh, you start with a three-dimensional scaffold that encourages cells to grow around them. These scaffolds are generally made of collagen, which makes up the connective tissue in almost every animal. The Harvard engineers basically took normal collagen, and wove nanowires and transistors into the matrix to create nanoelectric scaffolds (nanoES). The neurons, heart cells, muscle, and blood vessels were then grown as normal, creating cyborg tissue with a built-in sensor network.

So far the Havard team has mostly grown rat tissues, but they have also succeeded in growing a 1.5-centimeter (0.6in) cyborg human blood vessel. They’ve also only used the nanoelectric scaffolds to read data from the cells — but according to lead researcher Charles Lieber, the next step is to find a way of talking to the individual cells, to “wire up tissue and communicate with it in the same way a biological system does.”


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A computer chip, containing a sample of nanoES tissue

Suffice it to say, if you can use a digital computer to read and write data to your body’s cells, there are some awesome applications. If you need a quick jolt of adrenaline, you would simply tap a button on your smartphone, which is directly connected to your sympathetic nervous system. You could augment your existing physiology with patches — a patch of nanoelectric heart cells, for example, that integrates with your heart and reports back if you experience any problems. When we eventually put nanobots into our bloodstream, small pulses of electricity emitted by the cells could be used as guidance to damaged areas. In the case of blood vessels and other organs, the nanoelectric sensor network could detect if there’s inflammation, blockage, or tumors.

Realistically, though, we’re a long way away from such applications. In the short term, though, these cyborg tissues could be used to create very accurate organs-on-a-chip — lab-grown human organs that are encased within computer chips and then used to test drugs or substance toxicity, without harming a single bunny or bonobo.
 
Seems similar in concept to other tissues we've grown on artificial scaffolds, but with the added element of computerized monitoring equipment. Very cool!
 
Hm, I wonder how they handle foreign substance rejection.
Are the electronics just made by bio-suitable materials or are they simply ignored by the organism because they are nano-scaled?
 
I wonder if we'll ever get to the point where we'll be able to upload our "selves" into computer chips and download them into fetus's. Everyone could be immortal. Just a thought. Can't wait.
 
Hm, I wonder how they handle foreign substance rejection.
Are the electronics just made by bio-suitable materials or are they simply ignored by the organism because they are nano-scaled?

They must've solved it somehow, because "as far as the cells are concerned, they’re just normal cells that behave normally". If that's really the case, it's one major hurdle solved and they can focus on the individual cell communication.
 
I've always asked for this. Oh yessss.

Would have been perfect for first post, especially with dat avatar.

On-topic: great news, hopefully this tech is practical enough to see sustainable cells and maybe organs that can safely be implemented into the human body. We finally can make somebody stand up and leave the wheelchair behind.
 
They must've solved it somehow, because "as far as the cells are concerned, they’re just normal cells that behave normally". If that's really the case, it's one major hurdle solved and they can focus on the individual cell communication.

Might just be a new alloy then, or a matter of the electronics being too small to be targeted.
I'm kinda leaning towards to the latter explanation though, as nano drug delivery systems have shown potential for being "invisible" to the organism (in addition to breaching the brain-blood barrier).
 
25 now and reading these kinds of stories really motivates me to get healthier...who knows, maybe people my age have a shot at something really incredible down the line? I'm not talking ultra futuristic, but, who knows what 5 extra years can lead to?
 
Where do I sign-up for the testing?
 
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