Been really quiet on the 3DS front. Don't think they can come up with so much 3DS games at E3... Maybe 1/2/3. Majoras Mask 3D is possible... would like to see that to finally play it...
Other than that, can't think of many other 3DS games I'd want to see... Metroid for sure, but I'd much rather see them put that on Wii U first, but if they want to ignore it again, I'll take metroid however.
Other than them, can't think of much 3DS in really in "need of", other than more 3rd party things. A new 3D mario could be neat, a new NSMB, never got NSMB2 since it just seemed a rip at full price for what simply looked liked another NSMB DS.
They should really be focusing on Wii U at this E3, but if not, good ol' Nintendo I guess.