The first time'? I was a huge Resident Evil fan. I had been intrigued by the Hookman trailers, but I was never a fan of Leon. His entire schtick in RE2 was awful, and I find him to be the consistently poorest written and least charismatic main character in the series by far (an accomplishment in a series notorious for poor writing). So I was already apprehensive about the game from inception.
My living situation at the time was not affording me the best internet access, so when the direction changed, I was mostly unaware. All I remember were some message board murmurs of "no more zombies", and that was enough to get me really nervous.
I actually had to work solid the week it was released, so I didn't get to buy it until it was already 6 days old, but that didn't stop me from catching wind of all the praise. So when my day off came, I pulled some strings, cashed in a few favors, and made my way into town looking for a copy.
I loaded it up and... things went south fast. I believe I have already made my displeasure with the intro sequence made abundantly clear. At the time, it actually made me furious. Echoes of "no more zombies" bounded in my head, and I was further discouraged by the continued lack of anything resembling the Resident Evil I knew and loved. It only ever got worse. The shooting mechanics were fine, but shooting should never, ever be what Resident Evil is about. And all I did was shoot. My heart was breaking.
But I kept pushing through, hoping there would be something redeeming. I had made it as far as the fight with Salazar before I called foul. Not a single element that defined the series was present. It came across as a blatant "fuck you" from Mikami. He was evidently tired of Resident Evil and appeared to not really care about it anymore. He was going to make a different game and slap the name on it because the project had slogged on for too long. And everybody lapped it up.
I finished it. I wasn't happy, but I pushed through. I almost didn't give Mercenaries a chance, which is a shame, because it was easily the best part of the package. I felt at the time (and still do) that the shooting is a natural fit for that style of game even more than RE3's Mercenaries mode was. But these were just distractions, and never a part of why I played Resident Evil to begin with. What I had been left with was Shooter McGunsmack starring Leon. A style of gameplay I wasn't interested in starring scores of characters I didn't (couldn't) like.
To date, however, it has remained one of my most played "disliked" games. I will frequently replay to remind myself of places I had particular problem with so that my grievances will be fresh in my mind as I deride the game on the internet. I've actually bought it 3 times, interestingly enough. But in my annual playthroughs of the series that my girlfriend requests, I omit it from the line-up. I can only consider it the moment that the series died a spectacularly gruesome death, with it's lifeless corpse shuffling around like the zombies that once defined it.
I'm still bitter about it, and all the praise it continues to get even this long after everything it tried has been substantially improved upon in other games, leaves me with my jaw agape. Several times through, and I still can't see what you all see in it.
The game has some pitch perfect pacing, though. I'll give it that.