Would love them to rework Darkspore a little. I really enjoyed what I played of it, as sinful as that sounds in the eyes of the ever-snarling peanut gallery. Something so refreshing about lumbering around an alien landscape as a multi-legged xeno-creation, warping in teammates for savage combos. It did need a little in the way of random maps, just for longevity's sake...
I'd be up for a new Sim Isle, too! The memories. Sim Tower, of course.
But none of these are Triple A fodder. No. It'd have to be...
STREETS OF SIMCITY, MOTHERF@%KERS!