They rejected Washingtons direct counsel to the Delaware chiefs in 1779, You do well to wish to learn our arts and ways of life, and above all, the religion of Jesus Christ.
Thomas Jefferson three times signed legislation appropriating federal tax dollars for the evangelizing of the Native American tribes. It all came to nought, as one tribe after another rejected the offer of spiritual light and advanced civilization.
Missionaries were murdered in cold blood, including Marcus Whitman, who was tomahawked to death in his own house in 1848 by the Cayuse and Umatilla Indians in what became the Oregon Territory.
God explained to the nation of Israel that because of the abomination(s) of the indigenous Canaanite tribes, the land had become unclean and vomited out its inhabitants (Lev. 18:25).
Is this to say the same holds true for native American tribes today? In many respects, the answer is of course no. But in some senses, the answer is yes. Many of the tribal reservations today remain mired in poverty and alcoholism because many native Americans continue to cling to the darkness of indigenous superstition instead of coming into the light of Christianity and assimilating into Christian culture.