Street Fighter : The Movie (Arcade game):
I remember I saw this in an arcade in Greece and I couldn't believe how real it look like.
Toonstruck:
Real like actor (Christopher Loyd) in a Cartoon world ala Roger Rabbit.
Harvester:
A lot of point and click adventures blended in real life actors in the mid 90's. This is easily one of the fucked up games ever made.
Riven:
Looks good even today. Imagine how it was back in 1997
The Last Express:
It was a cartoon game, but they filmed and made everything with real actors then drew it in making all the characters look very real and lifelike. One of my favorite games of all time.
Phantasmagoria:
Again blending real actors who's performing in front of a bluescreen. This was the first FMV game I played, and it blew my mind back in the days.
Tex Murphy:
Tex Murphy went a slightly different way where they created complete 3D environments for you to explore in first person view and blended it in with FMV cutscenes.
The Black Dahlia:
One of the last FMV games to be made during the golden age of point and click adventures. This was probably one of the highest budged FMV game and came with like 8 CD's. (...and yes that is Dennis Hopper sitting in that chair in case you were wondering)