No. My phone is pushing four years old (iPhone 4) and the screen still looks fine with no more care than an occasional clean with a microfibre cloth. Unless you've got the superpower that allows you to put a screen protector on straight without any bubbles or dust underneath, they look like ass.
Eh it's really not that hard. But then again I feel like alot of people don't take their time when they put their screen protectors on.