My prediction for E3 this year:
Start
→ Video montage that shows only old/already announced games, Sackboy will do something funny, there will be one new game/character in this montage.
→ 'Momentum... PlayStation Family... PS Vita launch great, best software lineup of any launch ever'. Sony is also proud to have Netflix and Skype on their system. They're proud to have the Vita features, they're proud to be able to offer everything for free. They'll also mention that PS+ is a great success. Now they'll quickly mention that indie developers can now develop for a variety of PS branded systems. They'll also not forget to mention all the additional apps they've released on PSN (the photo app, music unlimited) and that one will also be shown in their video presentation.
It will be pointed out that Vita is the only gaming system where retail games get released day-in-date on the PSN. Customers are satisfied with that.
→ Another video montage. Sackboy will make funny faces.
→ Now it's about the games. Sony will announce spin-offs of their major franchises for PS Vita. There'll be a God of War, there will definitely be an EyePet game, and one game that no one expected. I could imagine something like the next David Cage project coming to Vita. They'll show Vita ports of console games and talk about the exclusive characters/DLC or something like that. They'll talk about many games currently in development.
They'll now show gameplay on stage (new, unannounced games).
→ Video Montage. Not 100% sure but Sackboy might appear to do something incredibly funny.
→ Let's shift to PS3. PlayStation 3 has, thanks to the amazing software lineup and free online, been doing great. No other platform offers the same experiences, no other platform offers that much variety.
→ Announcement of PS3 games. There will be a few Move enabled games but they'll all be from Sony third parties dropped the ball and will not make a single game exclusive to move (aside from PSN stuff). Sony will talk about Move numbers and how much inferior Move is to everything else.
→ Video Montage.
→ Someone will step on stage with a Vita in their hand. Now the release of the PSOne Emulator will be announced. It'll be either available right after the show or very soon after. Not all games will work right from the start. The person on stage will wait for applause nothing will happen.
Somewhere in between Sony will show games like The Last of Us, God of War, a new inFamous game, the Soul thing for Vita, The Last Guardian. TLG will come out this holiday season. FF versus XIII will not be shown or mentioned. Music wise, Sony will go the dubstep route this time around. Music will be way too loud, of course. The conference will start 15 minutes later than planned.