BoI Rebirth, Spelunky and Dragon's Crown were the best i tried from that list.
I wasn't impressed by the first Velocity games so i have no idea what 2X is worth. Might very well be the best thing ever but i probably will never know, my loss.
I heard good thing about Frozen Synapse sadly i didn't decided to give it a chance.
Hotline Miami was fun but... i dunno it didn't catch me that much either, outside of the OST which was really good, the Ai just felt idiotic and while i love tormenting them it just went to far.
Overall i'd say BoI:Rebirth is the best.
Dragon's Crown was fun and has enough content for a game of this gendra imo but even after my PS+ subscription ran out i didn't felt like taking it back yet (but i definitly will).
Spelunky is pretty good but i dunno, it just feels that the whole game is based on how annoying the shopkeepers are (of course they instantly die in the later stage so they are by far easier than the first, awesome design) so if i manage to get past the jungle and the black market i already won.
Also i don't like the scoring system at all, so i pretty never do ghosting. I can see the appeal but it's just not my thing, i just like to go from start to end.
Still a pretty good game i like playing now and then, glad i bought it last year.
Isaac controls well, the game had and still has clear issues (curse of the blind seriously...) but somes like enemy popping on top of you or broken rooms have been mostly purged (though some annoying stuff still exist, i personally find a few multi boss rooms broken, you realize it pretty quickly with a specific character). I dunno, i can play this game whenever i want, have fun and never really get bored.