On the AAA side of things, I'm pretty set on getting Diablo III: Ultimate Evil Edition, Destiny, and Dragon Age: Inquisition (unless they somehow turn out to be absolute garbage). I'm also interested in AC: Unity, LOTR: Shadow of Mordor, and Lords of the Fallen, but I'd rather wait and see how they turn out.
When it comes to indie stuff, it's hard to know what'll actually make it out this year, but the four releases I'm most anticipating most are The Witness, The Binding of Isaac: Rebirth, Hotline Miami 2, and Hyper Light Drifter.