I wouldn't hold my breath though.
Source: http://www.dualshockers.com/2017/04/03/bulletstorm-full-clip-edition-interview/DualShockers said:DualShockers: Is that also kind of a way that Duke could also come back in a new game of his? Is this a way for you guys to gauge interest in bringing him back for a new Duke Nukem game?
Vincent Slaven (Public Relations Manager, Gearbox Publishing): Not so much. It's pretty much like Meredith said that we were trying to think of things we could add to give more value to the customer: Duke Nukem came about [in Bulletstorm] because they were so similar.
But, kind of in relation to your question, this Full Clip Edition is more or less a way to do that — because People Can Fly own the rights to the franchise fully — and they want to do more with it. And so they are kind of like — because game development is so expensive — they want to put this out to see like ”Do people still want Bulletstorm?" Is there like a different climate now that would be more receptive? And if it is, there is definitely, probably gonna be an option for a Bulletstorm 2 following this.
So it's kind of not related but — Duke Nukem 2... no, but Bulletstorm 2, I think: maybe.