The best thing about WipEout is the soundtrack.
The best thing about F-Zero is the EVERYTHING.
Sorry to WipEout fans, but I personally choose the 60fps game with the better sense of speed (and higher speed, at that), the better and more responsive control, and without the lame (IMO) weapons.
That said, at least they are still (re-)releasing (old) games that say WipEout on them. Nintendo stupidly thinks that until they have some sort of new gimmick to sell us, there is no reason to make another F-Zero. Oh, I don't know, how about HD graphics and online play? Argh.