The new James has absolutely none of the clueless, bewildered tone that the earlier VA, however cheesy, absolutely nailed. Now he sounds like a one-testicled Solid Snake.
The new Maria sounds like a husky vixen instead of the slightly devilish, slightly sinister curious creature she should represent. She was obviously a vision of sex and lust, but it wasn't so overt before.
And I loved Mary's original voice. Compare the two VA jobs with the same exact lines - the original is innocent and serene, while the new one sounds like some random sultry-voiced babe.
No energy, and no charm to make up for it. But the games are in HD, so the VA could be done by the SoTN cast for all I care.