Ok, I'll go first with a game I discovered only recently. It's a Super Famicom Japanese only title called
Ghost Sweeper Mikami Joreishi wa Nice Body. It's based on a manga where you play a female who runs her own poltergeist hunting agency (kind of like a Japanese Ghostbusters). You can get a feel for the setting by watching the anime opening:
It's an action platformer made by the same people who brought us Ninja Warriors, so the gameplay is solid, if unoriginal. What sets it apart is the setting. The levels are set on spooky trains and deserted night time streets, and you get to fight a variety of ghoulish enemies, including zombies who get sliced in half and giant creepy dolls:
To top it off, you get Shinobi 3 style auto-scroll levels, but instead of riding a horse or a jet surf board you get to ride a giant cat!
The game isn't particularly difficult, so you should be able to complete it in a two or three hour evening session. Here is SNES Drunk's review, for those interested:
Oh, and the main character does appear to have a nice body, although I'm not sure why they felt the need to emphasise that fact in the title