Agreed, I even like Teen Titans GO but really dislike Powerpuff Girls.
Dunno about the new Powerpuff Girls series, but there's some interesting discussion there.
The original Powerpuff Girls wasn't originally meant to be a kid's show or a girl's show. It was meant to be an action/comedy series aimed at college students.
Look at the pilot, where they were called the Whoopass Girls, and Chemical X was a can of whoopass. Even in the final show, it was full of people getting their teeth knocked out, double entendres, references to pop culture from as far back as the sixties. There's an episode that's pretty much a biography of The Beatles.
However, the people marketing the show seemed to have no idea about this, and so all the merchandising treated it as if it was a normal cute girl's show. It had a shift in that direction in the last few seasons (might have been just one season, it's been a while) when the series creator Craig McCracken left.
In the vein of the original Powerpuff Girls, I feel like there's no reason why Mega Man can't succeed as a kids' show while being primarily built for an older audience, especially considering that it's mostly an action show. Although I don't have any data on kids' shows.
At it's core, the Mega Man series is based on a mix of Japanese tokusatsu shows, such as Power Rangers and Kamen Rider, as well as old-school shows such as Cashern.
That doesn't sound right to me. I think it's more:
Mega Man = Astro Boy
Protoman = Hakkaider (from Kikaider)
Mega Man X = Casshern
Mega Man Legends = Yatterman