Brawl - Can't touch Melee's jock strap.
Nintendo - How the fuck do you go through an entire generation without creating a new franchise? And no, I'm not counting the Wii X games. (Edit: Forgot about Blue Ocean, but still, they've done very little in this regard)
Microsoft - What's the plan here, guys? You've gradually lost numerous exclusives, you shut down at least one of your better developers (probably more I'm forgetting, but I miss FASA), Bungie is now third party, and future installments of your best exclusive franchise could be multi-platform or not on a Microsoft system at all if Epic chooses. All the while you charge for XBL, which I have little reason to pay for if without exclusives I can't play on PS3.
Splinter Cell - This was my favorite franchise last gen, and I hate the direction it's been going this gen. Also, no 2v2 Spies vs Mercs is a massive disappointment.