I don't know, I think an entirely adequate means of refining or deepening human experience is provided by meditation, and most augmentations that I can think of are pretty frivolous and insubstantial in terms of the happiness that they're likely to provide us in the larger scheme.
But meditation is hard, so I guess if there was something to provide the same effect while diminishing the requisite effort? But generally... mantis shrimp eyes and eidetic memory, etc, would be neat, but it's not going to solve any existential problems or make me a kinder or wiser individual. And I think that these are the crucial issues posed by human life, and there's already so much 'stuff' out there to distract me from this that I'm not really sure what I would gain from having yet more still, so from my perspective it's tangential to living a fulfilled life or not, and a negative if it becomes an obsession or source of craving.