This topic makes me remember an article I read in Reader's Digest a few weeks ago. There was this married couple who had been married for something like 20 years and had two kids in their teens. The wife discovered the husband one day trying on her clothes and lingerie and he came out to her that he (forgive me if my terminology is wrong) felt like a woman/was a woman in his (her?) mind and that now the secret was out in the open. So for a while, I guess they experimented with this, but the time eventually came when the husband wanted to go full-out and get surgery or the operation or whatever it was to complete the transformation. Afterwards, the wife was unable to cope and couldn't find herself attracted to him (her?) anymore and the marriage fell apart, even though they were still in love with each other, or at least the husband was still in love with the wife. Don't remember if she was still in love with the husband.
That story made me pretty sad