I've played about five hours so far, and I haven't really seen much of what the game has to offer yet, but here's what I've seen so far:
For the most part, the game does a good job of easing you into things. There really isn't what you'd call "high-level logic" in the style of designing circuits or anything. For the most part, you're laying out conveyor belts to lead to their associated factories and processing facilities. Everything so far has been a matter of "I need A and B to make C, but A requires C and D, while B requires C and E", then you adjust your production lines so that you can get everything together.
I've only gotten a few missions into what could be called the campaign so far (I think the fourth or fifth one, where you're tasked with restoring a rail system), and the last few missions have ended up being surprisingly long (or I just suck).
The one thing that sort of bugs me in the game is related to the research system. You see, in order to research things, you need to build labs, then make these various colored "science packs" (represented in-game by flasks with colored liquid) to then feed into the labs to do research. The initial research requires basic science packs, which are fairly straightforward to make. The next tier up requires some more intricate ingredients, so you have to set up a multi-stage production line, and so on.
So, with that in mind, once you decide what you want to research, you open up the research menu and click on it. Even the early stuff takes about 50 or so of the basic research packs to complete, so you of course set up a production line to produce a ton of the things, since that's what the game is about. However, this makes the research almost go so fast that you can't really appreciate each new technology learned. Once I've got my red science packs going, I'm able to research any technology requiring them in a matter of a minute or so, so I end up with a ton of new stuff available in a very short time, then I have to sit there and read about all of it, often overlooking some of the new toys.
I'm sure that won't matter as much once I get used to what everything is, but it is kind of offputting.