morningbus
Serious Sam is a wicked gahbidge series for chowdaheads.
Memes? Where?
I realize it wasn't direct towards me, but here is a list of just internet memes in the game (it features a ton of references):
Memes
Swag
Dr. Zed's vendors will randomly say "Who needs a medical license when you've got style?" A reference to the "Who needs 'X' When you've got swag?" Pictures
Cool story, bro
After getting a kill, Axton will occasionally say "Cool story, bro." This is a reference to the phrase used in response to a lengthy, off-track, or obviously fake story.
Similarly, the woman being talked at by a drunk outside Moxxi's will sometimes respond with "Super cool story, bro."
Killing Handsome Jack at the end of the game gives the "Cool Story, Bro" achievement.
Come At Me, Bro
When recharged the 1340 Shield will sometimes say " Come At Me." This is likely a reference to the meme Come At Me, Bro.
Don't Copy That Floppy
The second mission that C3n50r807 gives is titled "Don't Copy That Floppy", a reference to a viral video campaigning against software piracy.
Double Rainbow
The achievement "What does it mean?" is unlocked when seeing a double rainbow in the skies of The Highlands. This is a reference to a viral video of someone overly excited about a double rainbow.
Psychos will also occasionally shout "What could it all mean?" which is likely a reference to the "Double Rainbow" video.
Dragon Ball Z
The dials on each radio on Pandora show each hundred from 100 to 800. What should be "900" is actually "9001" in reference to the "It's over 9000" meme.
Haters Gonna Hate
The challenge "Haters Gonna Hate" is a reference to the meme of the same name.
Leeroy Jenkins
The challenge "JEEEEENKINSSSSSS!!!" is part of the famous phrase where he shouts his name and runs blindly into a dungeon in World of Warcraft.
Neil DeGrasse Tyson Reaction
While fighting a badass enemy after finding Lilith, she will sometimes say "Watch out, we've got a badass over here." This is a reference to the Neil DeGrasse Tyson meme of a similar title.
Pirates vs. Ninjas
In True Vault Hunter Mode, Corsairs in Captain Scarlett and Her Pirate's Booty are renamed Pirate Ninjas, a reference to the theoretical conflict between pirates and ninjas.
Shoop da Whoop
Constructors, before using their laser attack, will occasionally say "I'm charging mah lazer." a phrase associated with the "Shoop da Whoop" meme.
Super Cool Ski Instructor
One of the loading screen tips will say "if you fight a fire skag with a fire gun, you're gonna have a bad time." This is a reference to the South Park ski instructor meme.
U Mad?
The challenge 'U (No)Mad Bro?' is a reference to the "U MAD?" internet meme.
Xzibit Yo Dawg
One of the challenges is called "Yo Dawg, I heard you like challenges." in reference to the Xzibit meme.
Fuck Yeah
Some badass nomads (including Mad Mel) have a piece of metal with the Fuck Yeah meme on it attached to their shield.