Getting to your friends (and by default things like inviting to parties, sending messages, etc)
Getting to achievement leaderboard
Getting to your achievements
Getting to your last played game if you open an app (Before you had to flick down and press A, now it's flick down, flick right, A)
Getting to your notifications
Getting to your messages
Moving your pins around
And plenty more I'm sure. Seems like the only thing that's easier to get to in this update is moving more than one game to an external hard drive, which didn't need a UI change to happen.
I think the guide is better horizontally and it should be good/better than the old, I love the idea of being able to switch tabs in the guide while scrolling down without having to go back to the tabs again like you had to in the old one so that's definitely a step forward. But just about everything actually inside the guide is 2 steps backwards. Making switching tabs easier doesn't help when the information you want to see in those tabs isn't there any more without digging into menus. The old guide made horizontally would be near perfect.