Perhaps the most disappointing thing with the 3DS thus far is the lack of NEW content from talented development teams (particularly of the first party variety).
I love sequels as much as the next guy, but the 3DS lineup reads like that of every other Nintendo system. I'm happy to see a new Mario game, but wouldn't you also like to see, say, the team behind Zelda or some other group at EAD tackle a new game? Why were/are people excited for stuff like Uncharted, The Last Guardian, Bioshock, Shadows of the Damned, inFamous, Portal, Heavy Rain, Bayonetta, Mass Effect, Gears of War and Child of Eden? None of these series existed before this generation yet every one of them comes from a developer with a track record for producing amazing games. When you allow a talented team to come in and create something new the results are usually going to be incredible.
This is what I want to see out of Nintendo. I want to see the world class teams at EAD come up with something original yet in the spirit of games they've created previously. Zelda is a great series, but what about a new action adventure series from that group? It wouldn't have to play like Zelda, of course, but could be something of that magnitude and type. What about a new platformer with a unique mechanic, aesthetic, and level design from the Mario Galaxy team? I know these franchises are basically a license to print money, but it's disappointing seeing the exact same lineup of games once again on another platform. All the regulars are here. Why not allow at least one of those teams to create something original with the potential to become huge? They struck gold with the Wii* series of titles (Sports, Play, etc), but those really don't appeal in the same way that a good Zelda game does (at least to the non-casual crowd).
Let's see something new, Nintendo!