I do believe the fixed angles added to the atmosphere of the games and that something will be lost without them.
Here's the problem: if Capcom is genuinely capable of pulling off horror in over the shoulder... why haven't we seen it yet? Both Revelations games were designed to appeal to the horror fanbase as an alternative to the more action oriented core entries. Neither one came anywhere near the quality of the first three titles. So... why should we believe that Capcom redesigning the game in over the shoulder will work out here?
There are so many things that change when swapping the perspective. Your visibility is totally different: the idea of hearing enemies off-screen without knowing where they are would be jettisoned. There are a few licker scares in the RPD (both on the balconies of the RPD hall) that would be ruined in particular, where you'd be able to see the licker easily from a distance instead of blindly running straight into them.
Combat would also be totally different. Positioning would no longer be as important, as you'd be able to just shoot from any distance. In the original, you had to be close to a licker to kill it. With over the shoulder, why would you ever go within striking distance of one? You could always run away from an enemy, turn around and shoot it comfortably if you had the ability to free-aim, and unless they dramatically redesign the RPD (which no one wants), that will harm the gameplay. Think about it... how often did you run straight up to a licker in RE5? Did you pick them off from a safe distance, or run right up to them and leave yourself vulnerable before firing? Dogs would be shooting fish in a barrel, since they mostly appear in tight corridors and hitting them with free aim would be a cinch.
In fixed camera, you had to know the "zones" you could fire in. To hit a dog nearby, you had to aim down, but to hit them from a distance you had to fire straight. Knowing exactly when to aim which way was the difference between a dog tackling you or landing the shot. The same goes for lickers, which crawled with a low profile and forced you to aim downwards. There was a skill and tension in waiting for one to get near enough so you could blast it with a shotgun. Over the shoulder would ruin all of this.
The game was designed around fixed camera, and often it wouldn't translate to over the shoulder well. Think about how improbable wedging a game made for one perspective into another and having everything
still work is, and how unlikely it is that they'd be able to make it work without redesigning all of the encounters for the new camera and aiming system. As I said above, it wouldn't be RE2, even if it's a good game on its own.
We've waited too long for REmake 2 to get a different game. Let a new game use the over the shoulder camera. This game doesn't need to be ruined by wedging its environments, enemies, and general gameplay into a totally different control style. I say that as a huge fan of RE4. I can see some amount of novelty in playing RE2 that way, but I just don't see
why. Outside of the dated visuals, the game works as it is, just as REmake still works.